top of page

PUBLICATIONS

PUBLICATIONS

  1. Newton GL and Rawat M. 2019. N-methyl-bacillithiol, a Novel Thiol from Anaerobic Bacteria. MBio. 2019 Jan 15;10(1). pii: e02634-18. doi: 10.1128/mBio.02634-18.

  2. Mikheyeva IV, JM Thomas#, SL Kolar, AR Corvaglia, N Gaia, S Leo, P Francois, GY Lui, M Rawat, AL Cheung. 2019. YpdA, a putative bacillithiol disulfide reductase, contributes to cellular redox homeostasis and virulence in Staphylococcus aureus. Mol Microbiol. 2019. Jan 12. doi: 10.1111/mmi.14207.

  3. Van Laar TA, S Esani#, TJ Birges*, BC Hazen, JM Thomas*, 2018. Pseudomonas aeruginosa gshA mutant is defective in biofilm formation, swarming and pyocyanin production. mSphere. 3(2). e00155-18.

  4. Thomas JM*, N Ghebrendrias*, M Rawat. 2017. Genome sequences of two spore-forming bacteria isolated from the shore of Mono Lake, California. Genome Announc 5(10): e01742-16.

  5. Hillion M, J Bernhardt, T Buche, M Rossius, S Maas, D Becher, M Rawat, M Wirtz, R Hell, C Ruckert, J Kalinowski, H Antelmann. 2017. Monitoring global protein thiol-oxidation and protein S-mycothiolation in Mycobacterium smegmatis under hypochlorite stress.. Sci Rep. 7(1):1195-.1206.

  6. Kennedy V*, TA Van Laar, O Aleru*, M Thomas, M Ganci, 2016. Genome sequences of three spore-forming bacteria isolated from organically raised chicken feces. . 4(5). e00880-16.

  7. Singh AR, A Strankman#, R Orkusyan*, E Purwantini, . 2016. Lack of mycothiol and ergothioneine induce different protective mechanisms in . Biochem Biophys Rep 18:100-106.

  8. Vargas D#, S Hageman#, M Gulati, CJ. Nobile, . 2016. S-nitrosomycothiol reductase and mycothiol are required for survival under aldehyde stress and biofilm formation in . IUBMB Life. 68:621-628.

  9. Joseph JV, B Abejie, VK Diep*, M Gushiken, M Rawat, TR Tyner. 2013. The Synergetic Effect Of Ambient PM2 Exposure and Rhinovirus infection in airway dysfunction In asthma: A pilot observational study from the San Joaquin Valley, California. Exp Lung Res 39:434-440.

  10. Singh AR, A Strankman#, S Duran*, D Vargas#, AA Roberts, K Barretto*, H Upton*, CJ Hamilton, M Rawat. 2013. Analysis of mutants disrupted in bacillithiol metabolism in Staphylococcus aureus. Biochem Biophys Res Commun. 436:128-133.

  11. Roberts AA, SV Sharma, AW Strankman#, S Duran*, M Rawat, CJ Hamilton. 2013. Mechanistic studies of FosB: a divalent metal-dependent bacilithiol-S-transferase that mediates fosfomycin resistance in Stapylococcus aureus. Biochem J 451:69-79.

  12. Van Laer K.,L.Buts, K Van Belle, N Foloppe, G Roos,  L Nilsson, D Vertommen, K Wahni, M Rawat, NAJ Van Nuland, J Messens. 2012. Mycoredoxin-1 is one of the missing links in the oxidative stress defense mechanism of Mycobacterium tuberculosis. Mol. Microbiol. 86:787-804.

  13. Upton H*, GL Newton, MF Kane#, K Lo, D Holden, RC Fahey, M Rawat. 2012. BshA, a glycosyl transferase, catalyzes the first step in bacillithiol biosynthesis. FEBS Letters. 586:1004-1008.

  14. GL, RC Fahey, M Rawat. 2012. Detoxification of toxins by bacillithiol in Staphylococcus aureus. Microbiology. 158: 1117-1126.

  15. Newton GL, SS Leung, JI Wakabayashi#, M Rawat, RC Fahey. 2011. The DinB Superfamily Includes Novel Mycothiol, Bacillithiol and Glutathione S-transferases. Biochemistry. 50:10751-10760.

  16. Sharma SV, VK Jothivasan, GL Newton, H Upton*, JI Wakabayashi#, MG Kane#, AA Roberts, M Rawat, JJ La Clair, CJ Hamilton. 2011. Chemical and Chemoenzymatic Syntheses of Bacillithiol: A Unique Low-Molecular-Weight Thiol amongst Low G + C Gram-Positive Bacteria. Angew Chem Int Ed Engl. 50:7101-7104.

  17. Ta P, N Buchmeier, GL Newton, , RC Fahey. 2011. Organic hydroperoxide resistance protein and ergothioneine compensate for loss of mycothiol in mutants.

  18. Gaballa A, G Newton, H Antelmann, D Parsonage, H Upton*, , A Claiborne, RC Fahey, JD Helmann. 2010.  Biosynthesis of Bacillithiol and Function in Bacilli. Proceedings of the National Academy of Sciences.107:6482-6486.

  19. Newton GL, , J La Clair, V Jothivasan, T Budiarto, C Hamilton, A Claiborne, JD Helmann, RC. Fahey. 2009. Bacillithiol is an antioxidant thiol produced in Bacilli.. 5:625-627.

  20. Johnson T*, GL Newton, RC Fahey. 2009. Unusual production of glutathione in Actinobacteria. Archives of Microbiology 191:89-93.

  21. Rawat M, C. Johnson#, V. Cadiz#, Y Av-Gay. 2007. Comparative analysis of mutants disrupted in mycothiol biosynthesis. Biochemistry and Biophysical Research Communications. 363:71-76.

  22. Miller C, T Johnson*, , Y Av-Gay. 2007. Innate protection of against the antimicrobial activity of nitric oxide is provided by the low molecular weight thiol mycothiol. Antimicrobial Agents and Chemotherapy 5.

  23. Lopez D#, L Daniels, . 2007. mc² 155 fbiC and MSMEG_2391 are involved in triphenylmethane dye decolorization. Microbiology 153: 2724-2732.

  24. Rawat M, Y. Av-Gay. 2007. Mycothiol dependent proteins in Actinomycetes. FEMS Microbiology Reviews 31: 278-292.

  25. Pick N, , D. Arad, J. Lan, A. S. Kende. Y. Av-Gay. 2006. Antimicrobial properties of Bromo-Tyrosine Alkaloids. Journal of Medical Microbiology 55: 407-415.

  26. Dosanjh NS, , JH Li, Y. Av-Gay.2005. Thiol specific oxidative stress response in mycobacteria. FEMS Microbiology Letters 249:87-94.

  27. Rawat M, M Uppal*, GL Newton, M Steffek, RC Fahey, Y Av-Gay. 2004. Targeted mutagenesis of mycothiol amidase, a major detoxification enzyme in mycobacteria.  Journal of Bacteriology 186: 6050-6058.

  28. Newton GL, T Koledin, B Gorovitz, , RC Fahey, Y Av-Gay. 2003. The glucosyltransferase gene encoding the enzyme catalyzing the first step of mycothiol biosynthesis (mshA). Journal of Bacteriology.185:3476-3479.

  29. Rawat M, S Kovacevic, H Billman-Jacobe, Y Av-Gay. 2003. Inactivation of the mshB, a key gene in mycothiol biosynthesis pathway in Mycobacterium smegmatis. Microbiology 149:1341-1349.

  30. Rawat M, JM Heys*, Y Av-Gay. 2003.  Identification and characterization of a diamide sensitive mutant of Mycobacterium smegmatis. FEMS Microbiology Letters.220:161-169.

  31. Rawat M, GL Newton, M Ko, GJ Martinez, RC Fahey, Y AvGay. 2002. Mycothiol deficient mutants in Mycobacterium smegmatis are hypersensitive to alkylating agents, free radicals, and antibiotics. Antimicrobial Agents and Chemotherapy 46: 3348-3355.

  32. Ramazanov ZR, , CB Mason, and JV Moroney. 1996.Ultrastructural and biochemical adaptation of algal cells to limiting CO2 concentrations. Scientia Marina 60:141-148.

  33. Rawat M, MC Henk, LL Lavigne*, and JV Moroney. 1996.  Chlamydomonas reinhardtii mutants without ribulose-1,5-bisphosphate carboxylase-oxygenase lack a detectable pyrenoid. Planta 198:263-270.

  34. Henk MC, , SY Hugghins*, LL Lavigne*, Z Ramazanov, CB Mason, JV Moroney.1995. Pyrenoid morphology in rubisco and CO2 concentrating mutants of Chlamydomonas reinhardtii.Photosynthesis: From Light to Biosphere - Proceedings of the Xth International Photosynthesis Congress 5: 595-598.

  35. Rawat M, JV Moroney. 1995. Regulation of carbonic anhydrase and rubisco activase in Chlamydomonas reinhardtii.Plant Physiology 109:937-944.

  36. Ramazanov ZR, , MC Henk, CB Mason, SW Matthews, and JV Moroney. 1994. The induction of the CO2-concentrating mechanism is correlated with the formation of the starch sheath around the pyrenoid of Chlamydomonas reinhardtii. Planta 195:210-216.

  37. Robson P, GM Wright, E Sitarz, A Maiti, , JH Youson, FW Keeley. 1992. Characterization of lamprin, an unusual matrix protein from lamprey cartilage.Journal of Biological Chemistry 268:1440-1447.

  38. Rawat M, JV Moroney. 1991. Partial characterization of a new isoenzyme of carbonic anhydrase from Chlamydomonas reinhardtii.  Journal of Biological Chemistry. 266:9719-9723.

PATENTS

1.   Sareen D., GL Newton, RC. Fahey, N Buchmeier, M Steffek, Y Av-Gay, M Rawat, T Koledin, Methods of use of the enzymes of mycothiol synthesis. (Patent no. 7560229)

2.   Sareen D., GL Newton, RC. Fahey, N Buchmeier, M Steffek, Y Av-Gay, M Rawat, T Koledin, Methods of use of the enzymes of mycothiol synthesis. (PCT WO2003089585A2)

bottom of page